Rimonabant
Rimonabant is known under Zimulti and Acomplia brand names. It is used for obesity treatment. Rimonabant wasn’t approved in the USA yet and its usage is authorized only in European Union.
This medication is an example of new generation of drugs called Cannabinoid-1 Receptor Blockers. It acts in certain parts of brain which are responsible for body weight regulation and energy balance. Clinical tests have shown that Rimonabant not only reduces body weight but also improves the balance of cholesterol and sugar in the blood. It makes the drug especially effective for people with associated risk factors as diabetes. It is used for overweight treatment in people with Type 2 diabetes and abnormal level of fat in the blood. The mechanism of Rimonabant’s work affects pleasure centers of the brain helping to reduce the appetite. At the same way it causes moods changing and suicidal risk increase. This fact was one of the basic reasons why the drug wasn’t approved in the United States. It is also supposed that Rimonabant can help quit smoking.
Trials have shown that the most possible side effects of Rimonabant are nausea and vomiting. Also there were detected some psychiatric changes as panic, insomnia, anxiety and aggression.
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